Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions

Cholesterol is considered indispensable for cell motility, but how physiological cholesterol pools enable cells to move forward remains to be clarified. The majority of cells obtain cholesterol from the uptake of Low-Density lipoproteins (LDL) and here we demonstrate that LDL stimulates A431 squamou...

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Detalles Bibliográficos
Autores principales: Jose, Jaimy, Hoque, Monira, Engel, Johanna, Beevi, Syed S., Wahba, Mohamed, Georgieva, Mariya Ilieva, Murphy, Kendelle J., Hughes, William E., Cochran, Blake J., Lu, Albert, Tebar, Francesc, Hoy, Andrew J., Timpson, Paul, Rye, Kerry-Anne, Enrich, Carlos, Rentero, Carles, Grewal, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755831/
https://www.ncbi.nlm.nih.gov/pubmed/35022465
http://dx.doi.org/10.1038/s41598-021-04584-y

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