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Danger signal extracellular calcium initiates differentiation of monocytes into SPP1/osteopontin-producing macrophages

The danger signal extracellular calcium is pathophysiologically increased in the synovial fluid of patients with rheumatoid arthritis (RA). Calcium activates the NLRP3-inflammasome via the calcium-sensing receptor in monocytes/macrophages primed by lipopolysaccharide, and this effect is mediated by...

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Detalles Bibliográficos
Autores principales:	Murthy, Supriya, Karkossa, Isabel, Schmidt, Caroline, Hoffmann, Anne, Hagemann, Tobias, Rothe, Kathrin, Seifert, Olga, Anderegg, Ulf, von Bergen, Martin, Schubert, Kristin, Rossol, Manuela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755842/ https://www.ncbi.nlm.nih.gov/pubmed/35022393 http://dx.doi.org/10.1038/s41419-022-04507-3

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