The pannexin-1 channel regulates pyroptosis through autophagy in a mouse model of sepsis-associated encephalopathy

BACKGROUND: Sepsis-associated encephalopathy (SAE) is a diffuse brain dysfunction caused by sepsis. Pyroptosis and autophagy are important mechanisms in the pathogenesis of sepsis, and also pannexin-1 is involved in the occurrence of sepsis. However, role of pannexin-1 in SAE and its relationship wi...

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Detalles Bibliográficos
Autores principales: Lei, Yupeng, Zhou, Ruixi, Sun, Xuemei, Tang, Fajuan, Gao, Hu, Chen, Lin, Li, Xihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756244/
https://www.ncbi.nlm.nih.gov/pubmed/35071496
http://dx.doi.org/10.21037/atm-21-6579

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