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5-FU@DHA-UIO-66-NH(2) potentiates chemotherapy sensitivity of breast cancer cells through a microRNA let-7a-dependent mechanism

BACKGROUND: Drug delivery systems with magnetization facilitate the accumulation of drug at the target site. This study aimed to explore the mechanism by which docosahexaenoic acid (DHA)-modified porous metal-organic framework (MOF) UIO-66-NH(2) loads chemotherapeutic drug 5-fluorouracil (5-FU) and...

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Detalles Bibliográficos
Autores principales: Li, Jingquan, Lu, Fanghao, Shao, Xin, You, Bosen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756249/
https://www.ncbi.nlm.nih.gov/pubmed/35071455
http://dx.doi.org/10.21037/atm-21-5978