LncRNA MALAT1 induced by hyperglycemia promotes microvascular endothelial cell apoptosis through activation of the miR-7641/TPR axis to exacerbate neurologic damage caused by cerebral small vessel disease

BACKGROUND: This study aimed to explore the effect of hyperglycemia-induced long noncoding RNA (lncRNA) metastasis-associated lung carcinoma transcript 1 (MALAT1) on microvascular endothelial cell activity. In addition, we investigated the possible downstream molecular regulatory mechanism in order...

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Detalles Bibliográficos
Autores principales: Che, Fei, Han, Yunfeng, Fu, Jinxia, Wang, Nannan, Jia, Yuehui, Wang, Kun, Ge, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756250/
https://www.ncbi.nlm.nih.gov/pubmed/35071456
http://dx.doi.org/10.21037/atm-21-5997

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