The translocator protein gene is associated with endogenous pain modulation and the balance between glutamate and γ-aminobutyric acid in fibromyalgia and healthy subjects: a multimodal neuroimaging study

A cerebral upregulation of the translocator protein (TSPO), a biomarker of glial activation, has been reported in fibromyalgia subjects (FMS). The TSPO binding affinity is genetically regulated by the Ala147Thr polymorphism in the TSPO gene (rs6971) and allows for a subject classification into high...

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Detalles Bibliográficos
Autores principales: Fanton, Silvia, Sandström, Angelica, Tour, Jeanette, Kadetoff, Diana, Schalling, Martin, Jensen, Karin B., Sitnikov, Rouslan, Ellerbrock, Isabel, Kosek, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756347/
https://www.ncbi.nlm.nih.gov/pubmed/34142769
http://dx.doi.org/10.1097/j.pain.0000000000002309

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