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Changes to the activity and sensitivity of nerves innervating subchondral bone contribute to pain in late-stage osteoarthritis
Although it is clear that osteoarthritis (OA) pain involves activation and/or sensitization of nociceptors that innervate knee joint articular tissues, much less is known about the role of the innervation of surrounding bone. In this study, we used monoiodoacetate (MIA)-induced OA in male rats to te...
Autores principales: | Morgan, Michael, Thai, Jenny, Nazemian, Vida, Song, Richard, Ivanusic, Jason J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756348/ https://www.ncbi.nlm.nih.gov/pubmed/34108432 http://dx.doi.org/10.1097/j.pain.0000000000002355 |
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