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Changes to the activity and sensitivity of nerves innervating subchondral bone contribute to pain in late-stage osteoarthritis

Although it is clear that osteoarthritis (OA) pain involves activation and/or sensitization of nociceptors that innervate knee joint articular tissues, much less is known about the role of the innervation of surrounding bone. In this study, we used monoiodoacetate (MIA)-induced OA in male rats to te...

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Detalles Bibliográficos
Autores principales: Morgan, Michael, Thai, Jenny, Nazemian, Vida, Song, Richard, Ivanusic, Jason J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756348/
https://www.ncbi.nlm.nih.gov/pubmed/34108432
http://dx.doi.org/10.1097/j.pain.0000000000002355

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