Diketomorpholines: Synthetic Accessibility and Utilization

[Image: see text] Diketomorpholines (DKMs; morpholine-2,5-diones) possess a six-membered ring with a lactone and lactam moiety and belong to the family of cyclodepsipeptides. In this review, the synthetic accessibility of DKMs is summarized and their utilization, in particular, for ring-opening poly...

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Autores principales: Vu, Lan Phuong, Gütschow, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756451/
https://www.ncbi.nlm.nih.gov/pubmed/35036677
http://dx.doi.org/10.1021/acsomega.1c05964
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author Vu, Lan Phuong
Gütschow, Michael
author_facet Vu, Lan Phuong
Gütschow, Michael
author_sort Vu, Lan Phuong
collection PubMed
description [Image: see text] Diketomorpholines (DKMs; morpholine-2,5-diones) possess a six-membered ring with a lactone and lactam moiety and belong to the family of cyclodepsipeptides. In this review, the synthetic accessibility of DKMs is summarized and their utilization, in particular, for ring-opening polymerization reactions, is highlighted. The occurrence of the DKM scaffold in natural products encompasses small monocyclic compounds but also complex, polycyclic representatives with a fused DKM ring.
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spelling pubmed-87564512022-01-13 Diketomorpholines: Synthetic Accessibility and Utilization Vu, Lan Phuong Gütschow, Michael ACS Omega [Image: see text] Diketomorpholines (DKMs; morpholine-2,5-diones) possess a six-membered ring with a lactone and lactam moiety and belong to the family of cyclodepsipeptides. In this review, the synthetic accessibility of DKMs is summarized and their utilization, in particular, for ring-opening polymerization reactions, is highlighted. The occurrence of the DKM scaffold in natural products encompasses small monocyclic compounds but also complex, polycyclic representatives with a fused DKM ring. American Chemical Society 2021-12-22 /pmc/articles/PMC8756451/ /pubmed/35036677 http://dx.doi.org/10.1021/acsomega.1c05964 Text en © 2021 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Vu, Lan Phuong
Gütschow, Michael
Diketomorpholines: Synthetic Accessibility and Utilization
title Diketomorpholines: Synthetic Accessibility and Utilization
title_full Diketomorpholines: Synthetic Accessibility and Utilization
title_fullStr Diketomorpholines: Synthetic Accessibility and Utilization
title_full_unstemmed Diketomorpholines: Synthetic Accessibility and Utilization
title_short Diketomorpholines: Synthetic Accessibility and Utilization
title_sort diketomorpholines: synthetic accessibility and utilization
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756451/
https://www.ncbi.nlm.nih.gov/pubmed/35036677
http://dx.doi.org/10.1021/acsomega.1c05964
work_keys_str_mv AT vulanphuong diketomorpholinessyntheticaccessibilityandutilization
AT gutschowmichael diketomorpholinessyntheticaccessibilityandutilization

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