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TIGAR-V2: Efficient TWAS tool with nonparametric Bayesian eQTL weights of 49 tissue types from GTEx V8
Standard transcriptome-wide association study (TWAS) methods first train gene expression prediction models using reference transcriptomic data and then test the association between the predicted genetically regulated gene expression and phenotype of interest. Most existing TWAS tools require cumbers...
Autores principales: | Parrish, Randy L., Gibson, Greg C., Epstein, Michael P., Yang, Jingjing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756507/ https://www.ncbi.nlm.nih.gov/pubmed/35047855 http://dx.doi.org/10.1016/j.xhgg.2021.100068 |
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