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Genome-wide survey of parent-of-origin-specific associations across clinical traits derived from electronic health records
Parent-of-origin (PoO) effects refer to the differential phenotypic impacts of genetic variants dependent on their parental inheritance due to imprinting. While PoO effects can influence complex traits, they may be poorly captured by models that do not differentiate the parental origin of the varian...
Autores principales: | Kim, Hye In, Ye, Bin, Staples, Jeffrey, Marcketta, Anthony, Gao, Chuan, Shuldiner, Alan R., Van Hout, Cristopher V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756508/ https://www.ncbi.nlm.nih.gov/pubmed/35047837 http://dx.doi.org/10.1016/j.xhgg.2021.100039 |
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