Microplasma-Enabled Surfaced-Functionalized Silicon Quantum Dots for Label-Free Detection of Dopamine

[Image: see text] Rapid and sensitive detection of dopamine (DA) is important for the diagnostics of neurological disorders and the development of new drugs. Here, we report microplasma synthesis of surfaced-functionalized silicon quantum dots (SiQDs) at ambient conditions. The synthesized SiQDs wit...

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Autores principales: Chang, Gui-Yi, Kurniawan, Darwin, Chang, Yi-Ju, Chiang, Wei-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756587/
https://www.ncbi.nlm.nih.gov/pubmed/35036694
http://dx.doi.org/10.1021/acsomega.1c04467
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author Chang, Gui-Yi
Kurniawan, Darwin
Chang, Yi-Ju
Chiang, Wei-Hung
author_facet Chang, Gui-Yi
Kurniawan, Darwin
Chang, Yi-Ju
Chiang, Wei-Hung
author_sort Chang, Gui-Yi
collection PubMed
description [Image: see text] Rapid and sensitive detection of dopamine (DA) is important for the diagnostics of neurological disorders and the development of new drugs. Here, we report microplasma synthesis of surfaced-functionalized silicon quantum dots (SiQDs) at ambient conditions. The synthesized SiQDs with useful properties including abundant surface functionalities, stable colloidal dispersion, and photoluminescence (PL) emission enable direct label-free detection of DA, providing a wide sensing range from 0.83 to 83.33 μM and a low detection limit of 0.32 μM. Our work provides a new direction for the synthesis of colloidal SiQDs and the understanding of SiQD-based PL probes for biomolecule sensing.
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spelling pubmed-87565872022-01-13 Microplasma-Enabled Surfaced-Functionalized Silicon Quantum Dots for Label-Free Detection of Dopamine Chang, Gui-Yi Kurniawan, Darwin Chang, Yi-Ju Chiang, Wei-Hung ACS Omega [Image: see text] Rapid and sensitive detection of dopamine (DA) is important for the diagnostics of neurological disorders and the development of new drugs. Here, we report microplasma synthesis of surfaced-functionalized silicon quantum dots (SiQDs) at ambient conditions. The synthesized SiQDs with useful properties including abundant surface functionalities, stable colloidal dispersion, and photoluminescence (PL) emission enable direct label-free detection of DA, providing a wide sensing range from 0.83 to 83.33 μM and a low detection limit of 0.32 μM. Our work provides a new direction for the synthesis of colloidal SiQDs and the understanding of SiQD-based PL probes for biomolecule sensing. American Chemical Society 2021-11-26 /pmc/articles/PMC8756587/ /pubmed/35036694 http://dx.doi.org/10.1021/acsomega.1c04467 Text en © 2021 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Chang, Gui-Yi
Kurniawan, Darwin
Chang, Yi-Ju
Chiang, Wei-Hung
Microplasma-Enabled Surfaced-Functionalized Silicon Quantum Dots for Label-Free Detection of Dopamine
title Microplasma-Enabled Surfaced-Functionalized Silicon Quantum Dots for Label-Free Detection of Dopamine
title_full Microplasma-Enabled Surfaced-Functionalized Silicon Quantum Dots for Label-Free Detection of Dopamine
title_fullStr Microplasma-Enabled Surfaced-Functionalized Silicon Quantum Dots for Label-Free Detection of Dopamine
title_full_unstemmed Microplasma-Enabled Surfaced-Functionalized Silicon Quantum Dots for Label-Free Detection of Dopamine
title_short Microplasma-Enabled Surfaced-Functionalized Silicon Quantum Dots for Label-Free Detection of Dopamine
title_sort microplasma-enabled surfaced-functionalized silicon quantum dots for label-free detection of dopamine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756587/
https://www.ncbi.nlm.nih.gov/pubmed/35036694
http://dx.doi.org/10.1021/acsomega.1c04467
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