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Pharmacophore-Based Virtual Screening and Molecular Dynamics Simulation for Identification of a Novel DNA Gyrase B Inhibitor with Benzoxazine Acetamide Scaffold

[Image: see text] DNA gyrase B is one of the enzyme targets for antimicrobial drug development, and its absence in mammals makes it a suitable target for the creation of safe antibacterial drugs. We identified six novel hits as DNA gyrase B inhibitors in the present study by employing 3D-pharmacopho...

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Detalles Bibliográficos
Autores principales:	Elseginy, Samia A., Anwar, Manal M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756603/ https://www.ncbi.nlm.nih.gov/pubmed/35036778 http://dx.doi.org/10.1021/acsomega.1c05732

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