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Characterization and use of the ECV304 autoantigenic citrullinome to understand anti-citrullinated protein/peptide autoantibodies in rheumatoid arthritis

BACKGROUND: Anti-citrullinated protein antibodies (ACPAs) are highly specific for rheumatoid arthritis (RA). In vivo, ACPAs target peptidyl-citrulline epitopes (cit-) in a variety of proteins (cit-prot-ACPAs) and derived peptides (cit-pept-ACPAs) generated via the peptidylarginine deiminase (PAD) is...

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Detalles Bibliográficos
Autores principales:	de França, Natalia Regine, Ménard, Henri André, Lora, Maximilien, Zhou, Zhijie, Rauch, Joyce, Hitchon, Carol, Andrade, Luís Eduardo Coelho, Colmegna, Inés
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756661/ https://www.ncbi.nlm.nih.gov/pubmed/35027076 http://dx.doi.org/10.1186/s13075-021-02698-2

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