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Extracellular vesicles derived from glioblastoma promote proliferation and migration of neural progenitor cells via PI3K-Akt pathway

BACKGROUND: Glioblastomas are lethal brain tumors under the current combinatorial therapeutic strategy that includes surgery, chemo- and radio-therapies. Extensive changes in the tumor microenvironment is a key reason for resistance to chemo- or radio-therapy and frequent tumor recurrences. Understa...

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Detalles Bibliográficos
Autores principales: Pan, Jiabin, Sheng, Shiyang, Ye, Ling, Xu, Xiaonan, Ma, Yizhao, Feng, Xuanran, Qiu, Lisha, Fan, Zhaohuan, Wang, Yi, Xia, Xiaohuan, Zheng, Jialin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756733/
https://www.ncbi.nlm.nih.gov/pubmed/35022057
http://dx.doi.org/10.1186/s12964-021-00760-9