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StarD13 negatively regulates invadopodia formation and invasion in high-grade serous (HGS) ovarian adenocarcinoma cells by inhibiting Cdc42

Metastasis remains the main challenge to overcome for treating ovarian cancers. In this study, we investigate the potential role of the Cdc42 GAP StarD13 in the modulation of cell motility, invasion in ovarian cancer cells. StarD13 depletion does not affect the 2D motility of ovarian cancer cells. M...

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Detalles Bibliográficos
Autores principales: Abdellatef, Sandra, Fakhoury, Isabelle, Al Haddad, Maria, Jaafar, Leila, Maalouf, Hiba, Hanna, Samer, Khalil, Bassem, El Masri, Zeinab, Hodgson, Louis, El-Sibai, Mirvat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8756770/
https://www.ncbi.nlm.nih.gov/pubmed/34958986
http://dx.doi.org/10.1016/j.ejcb.2021.151197

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