Timing of selective basal ganglia white matter loss in premanifest Huntington’s disease

OBJECTIVES: To investigate the timeframe prior to symptom onset when cortico-basal ganglia white matter (white matter) loss begins in premanifest Huntington’s disease (preHD), and which striatal and thalamic sub-region white matter tracts are most vulnerable. METHODS: We performed fixel-based analys...

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Detalles Bibliográficos
Autores principales: Zeun, Paul, McColgan, Peter, Dhollander, Thijs, Gregory, Sarah, Johnson, Eileanoir B., Papoutsi, Marina, Nair, Akshay, Scahill, Rachael I., Rees, Geraint, Tabrizi, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757039/
https://www.ncbi.nlm.nih.gov/pubmed/34999565
http://dx.doi.org/10.1016/j.nicl.2021.102927

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