Protective effects of farnesyltransferase inhibitor on sepsis-induced morphological aberrations of mitochondria in muscle and increased circulating mitochondrial DNA levels in mice

Sepsis remains a leading cause of mortality in critically ill patients and is characterized by multi-organ dysfunction. Mitochondrial damage has been proposed to be involved in the pathophysiology of sepsis. In addition to metabolic impairments resulting from mitochondrial dysfunction, mitochondrial...

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Detalles Bibliográficos
Autores principales: Tsuji, Daisuke, Nakazawa, Harumasa, Yorozu, Tomoko, Kaneki, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757346/
https://www.ncbi.nlm.nih.gov/pubmed/33845310
http://dx.doi.org/10.1016/j.bbrc.2021.03.141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757346/
https://www.ncbi.nlm.nih.gov/pubmed/33845310
http://dx.doi.org/10.1016/j.bbrc.2021.03.141

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