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Characteristics and Stability Assessment of Therapeutic Methionine γ-lyase-Loaded Polyionic Vesicles

[Image: see text] Pyridoxal 5′-phosphate-dependent methionine γ-lyase from Citrobacter freundii (MGL, EC 4.4.1.11) is studied as an antitumor enzyme and in combination with substrates as an antibacterial agent in enzyme pro-drug therapy. For the possibility of in vivo trials, two mutant forms, C115H...

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Detalles Bibliográficos
Autores principales: Koval, Vasily, Morozova, Elena, Revtovich, Svetlana, Lyfenko, Anna, Chobanian, Arpi, Timofeeva, Viktoria, Solovieva, Anna, Anufrieva, Natalya, Kulikova, Vitalia, Demidkina, Tatyana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757458/
https://www.ncbi.nlm.nih.gov/pubmed/35036759
http://dx.doi.org/10.1021/acsomega.1c05558