MerTK-mediated efferocytosis promotes immune tolerance and tumor progression in osteosarcoma through enhancing M2 polarization and PD-L1 expression

The poor progress of immunotherapy on osteosarcoma patients requires deeper delineation of immune tolerance mechanisms in the osteosarcoma microenvironment and a new therapeutic strategy. Clearance of apoptotic cells by phagocytes, a process termed “efferocytosis,” is ubiquitous in tumors and mediat...

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Detalles Bibliográficos
Autores principales: Lin, Jinti, Xu, Ankai, Jin, Jiakang, Zhang, Man, Lou, Jianan, Qian, Chao, Zhu, Jian, Wang, Yitian, Yang, Zhengming, Li, Xiumao, Yu, Wei, Liu, Bing, Tao, Huimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757471/
https://www.ncbi.nlm.nih.gov/pubmed/35036076
http://dx.doi.org/10.1080/2162402X.2021.2024941

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