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Evaluating the impact of age on immune checkpoint therapy biomarkers

Both tumors and aging alter the immune landscape of tissues. These interactions may play an important role in tumor progression among elderly patients and may suggest considerations for patient care. We leverage large-scale genomic and clinical databases to perform comprehensive comparative analysis...

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Detalles Bibliográficos
Autores principales:	Erbe, Rossin, Wang, Zheyu, Wu, Sharon, Xiu, Joanne, Zaidi, Neeha, La, Jennifer, Tuck, David, Fillmore, Nathanael, Giraldo, Nicolas A., Topper, Michael, Baylin, Stephen, Lippman, Marc, Isaacs, Claudine, Basho, Reva, Serebriiskii, Ilya, Lenz, Heinz-Josef, Astsaturov, Igor, Marshall, John, Taverna, Josephine, Lee, Jerry, Jaffee, Elizabeth M., Torres, Evanthia T. Roussos, Weeraratna, Ashani, Easwaran, Hariharan, Fertig, Elana J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757482/ https://www.ncbi.nlm.nih.gov/pubmed/34433020 http://dx.doi.org/10.1016/j.celrep.2021.109599

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