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Multi-stage structure-based virtual screening approach towards identification of potential SARS-CoV-2 NSP13 helicase inhibitors

On account of its crucial role in the virus life cycle, SARS-COV-2 NSP13 helicase enzyme was exploited as a promising target to identify a novel potential inhibitor using multi-stage structure-based drug discovery approaches. Firstly, a 3D pharmacophore was generated based on the collected data from...

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Detalles Bibliográficos
Autores principales:	El Hassab, Mahmoud A., Eldehna, Wagdy M., Al-Rashood, Sara T., Alharbi, Amal, Eskandrani, Razan O., Alkahtani, Hamad M., Elkaeed, Eslam B., Abou-Seri, Sahar M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757614/ https://www.ncbi.nlm.nih.gov/pubmed/35012384 http://dx.doi.org/10.1080/14756366.2021.2022659

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