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Vps13-like proteins provide phosphatidylethanolamine for GPI anchor synthesis in the ER

Glycosylphosphatidylinositol (GPI) is a glycolipid membrane anchor found on surface proteins in all eukaryotes. It is synthesized in the ER membrane. Each GPI anchor requires three molecules of ethanolamine phosphate (P-Etn), which are derived from phosphatidylethanolamine (PE). We found that effici...

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Detalles Bibliográficos
Autores principales:	Toulmay, Alexandre, Whittle, Fawn B., Yang, Jerry, Bai, Xiaofei, Diarra, Jessica, Banerjee, Subhrajit, Levine, Tim P., Golden, Andy, Prinz, William A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2022
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757616/ https://www.ncbi.nlm.nih.gov/pubmed/35015055 http://dx.doi.org/10.1083/jcb.202111095

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