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Strategies to minimize heterogeneity and optimize clinical trials in Acute Respiratory Distress Syndrome (ARDS): Insights from mathematical modelling
BACKGROUND: Mathematical modelling may aid in understanding the complex interactions between injury and immune response in critical illness. METHODS: We utilize a system biology model of COVID-19 to analyze the effect of altering baseline patient characteristics on the outcome of immunomodulatory th...
Autores principales: | Subudhi, Sonu, Voutouri, Chrysovalantis, Hardin, C. Corey, Nikmaneshi, Mohammad Reza, Patel, Ankit B., Verma, Ashish, Khandekar, Melin J., Dutta, Sayon, Stylianopoulos, Triantafyllos, Jain, Rakesh K., Munn, Lance L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757652/ https://www.ncbi.nlm.nih.gov/pubmed/35033853 http://dx.doi.org/10.1016/j.ebiom.2021.103809 |
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