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Effectiveness of the Conservative Surgical Management of the Ameloblastomas: A Cross-Sectional Study

Ameloblastoma is a benign, but locally aggressive odontogenic neoplasm, whose appropriate therapeutic management remains highly debatable. The aim of this study was to evaluate the reliability and effectiveness of the two conservative surgical therapeutic protocols (curettage with peripheral ostecto...

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Autores principales: Rocha, André Caroli, Fonseca, Felipe Paiva, Santos-Silva, Alan Roger, Lourenço, Silvia Vanessa, Ceccheti, Marcelo Minharro, Júnior, Jayro Guimarães
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757795/
https://www.ncbi.nlm.nih.gov/pubmed/35048054
http://dx.doi.org/10.3389/froh.2021.737424
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author Rocha, André Caroli
Fonseca, Felipe Paiva
Santos-Silva, Alan Roger
Lourenço, Silvia Vanessa
Ceccheti, Marcelo Minharro
Júnior, Jayro Guimarães
author_facet Rocha, André Caroli
Fonseca, Felipe Paiva
Santos-Silva, Alan Roger
Lourenço, Silvia Vanessa
Ceccheti, Marcelo Minharro
Júnior, Jayro Guimarães
author_sort Rocha, André Caroli
collection PubMed
description Ameloblastoma is a benign, but locally aggressive odontogenic neoplasm, whose appropriate therapeutic management remains highly debatable. The aim of this study was to evaluate the reliability and effectiveness of the two conservative surgical therapeutic protocols (curettage with peripheral ostectomy only and curettage plus cryotherapy) for the management of ameloblastomas. About 53 cases of the ameloblastomas treated in 9 years were retrospectively analyzed regarding their clinical, histopathologic, radiographic, and therapeutic data. The results and the postoperative complications related to both the therapeutic protocols were also statistically investigated. A slight female preponderance was seen (1.12:1.0) with a mean age of 27.1 years. The posterior mandible was the most affected site and dental involvement was frequently found. Multilocular lesions causing the alterations of the bone cortices were the most common radiographic findings. Recurrences were seen in 9.4% of the cases and although the patients submitted to curettage plus cryotherapy have shown an increased incidence of wound dehiscence, infection, and paresthesia, only bone sequestration proved to be significantly more frequent in this group compared to the patients treated by curettage with peripheral ostectomy only. The incidence of the recurrences following the conservative management is low and cryotherapy use as an adjuvant tool must be rationally considered.
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spelling pubmed-87577952022-01-18 Effectiveness of the Conservative Surgical Management of the Ameloblastomas: A Cross-Sectional Study Rocha, André Caroli Fonseca, Felipe Paiva Santos-Silva, Alan Roger Lourenço, Silvia Vanessa Ceccheti, Marcelo Minharro Júnior, Jayro Guimarães Front Oral Health Oral Health Ameloblastoma is a benign, but locally aggressive odontogenic neoplasm, whose appropriate therapeutic management remains highly debatable. The aim of this study was to evaluate the reliability and effectiveness of the two conservative surgical therapeutic protocols (curettage with peripheral ostectomy only and curettage plus cryotherapy) for the management of ameloblastomas. About 53 cases of the ameloblastomas treated in 9 years were retrospectively analyzed regarding their clinical, histopathologic, radiographic, and therapeutic data. The results and the postoperative complications related to both the therapeutic protocols were also statistically investigated. A slight female preponderance was seen (1.12:1.0) with a mean age of 27.1 years. The posterior mandible was the most affected site and dental involvement was frequently found. Multilocular lesions causing the alterations of the bone cortices were the most common radiographic findings. Recurrences were seen in 9.4% of the cases and although the patients submitted to curettage plus cryotherapy have shown an increased incidence of wound dehiscence, infection, and paresthesia, only bone sequestration proved to be significantly more frequent in this group compared to the patients treated by curettage with peripheral ostectomy only. The incidence of the recurrences following the conservative management is low and cryotherapy use as an adjuvant tool must be rationally considered. Frontiers Media S.A. 2021-10-29 /pmc/articles/PMC8757795/ /pubmed/35048054 http://dx.doi.org/10.3389/froh.2021.737424 Text en Copyright © 2021 Rocha, Fonseca, Santos-Silva, Lourenço, Ceccheti and Júnior. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oral Health
Rocha, André Caroli
Fonseca, Felipe Paiva
Santos-Silva, Alan Roger
Lourenço, Silvia Vanessa
Ceccheti, Marcelo Minharro
Júnior, Jayro Guimarães
Effectiveness of the Conservative Surgical Management of the Ameloblastomas: A Cross-Sectional Study
title Effectiveness of the Conservative Surgical Management of the Ameloblastomas: A Cross-Sectional Study
title_full Effectiveness of the Conservative Surgical Management of the Ameloblastomas: A Cross-Sectional Study
title_fullStr Effectiveness of the Conservative Surgical Management of the Ameloblastomas: A Cross-Sectional Study
title_full_unstemmed Effectiveness of the Conservative Surgical Management of the Ameloblastomas: A Cross-Sectional Study
title_short Effectiveness of the Conservative Surgical Management of the Ameloblastomas: A Cross-Sectional Study
title_sort effectiveness of the conservative surgical management of the ameloblastomas: a cross-sectional study
topic Oral Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757795/
https://www.ncbi.nlm.nih.gov/pubmed/35048054
http://dx.doi.org/10.3389/froh.2021.737424
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