The Path to an Evidence-Based Treatment Protocol for Extraoral Photobiomodulation Therapy for the Prevention of Oral Mucositis

Oral mucositis is a painful complication of hematopoietic stem cell transplantation for which photobiomodulation therapy (PBMT) is a safe and effective intervention. Extraoral delivery of PBMT has clinical advantages over intraoral delivery but requires additional dosimetric considerations due to th...

Descripción completa

Detalles Bibliográficos
Autores principales: Adnan, Ather, Yaroslavsky, Anna N., Carroll, James D., Selting, Wayne, Juliano, Amy F., London, Wendy B., Sonis, Stephen T., Duncan, Christine N., Treister, Nathaniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oral Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757848/
https://www.ncbi.nlm.nih.gov/pubmed/35048034
http://dx.doi.org/10.3389/froh.2021.689386
_version_ 1784632770480308224
author Adnan, Ather
Yaroslavsky, Anna N.
Carroll, James D.
Selting, Wayne
Juliano, Amy F.
London, Wendy B.
Sonis, Stephen T.
Duncan, Christine N.
Treister, Nathaniel S.
author_facet Adnan, Ather
Yaroslavsky, Anna N.
Carroll, James D.
Selting, Wayne
Juliano, Amy F.
London, Wendy B.
Sonis, Stephen T.
Duncan, Christine N.
Treister, Nathaniel S.
author_sort Adnan, Ather
collection PubMed
description Oral mucositis is a painful complication of hematopoietic stem cell transplantation for which photobiomodulation therapy (PBMT) is a safe and effective intervention. Extraoral delivery of PBMT has clinical advantages over intraoral delivery but requires additional dosimetric considerations due to the external tissue layers through which the light must propagate before reaching the oral mucosa. Additionally, to date there has been no dose modeling study, a task essential to developing a justified treatment protocol. We review here some of the complexities surrounding extraoral photobiomodulation therapy and offer that may help guide researchers toward an evidence-based treatment protocol for the prevention of oral mucositis.
format Online
Article
Text
id pubmed-8757848
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-87578482022-01-18 The Path to an Evidence-Based Treatment Protocol for Extraoral Photobiomodulation Therapy for the Prevention of Oral Mucositis Adnan, Ather Yaroslavsky, Anna N. Carroll, James D. Selting, Wayne Juliano, Amy F. London, Wendy B. Sonis, Stephen T. Duncan, Christine N. Treister, Nathaniel S. Front Oral Health Oral Health Oral mucositis is a painful complication of hematopoietic stem cell transplantation for which photobiomodulation therapy (PBMT) is a safe and effective intervention. Extraoral delivery of PBMT has clinical advantages over intraoral delivery but requires additional dosimetric considerations due to the external tissue layers through which the light must propagate before reaching the oral mucosa. Additionally, to date there has been no dose modeling study, a task essential to developing a justified treatment protocol. We review here some of the complexities surrounding extraoral photobiomodulation therapy and offer that may help guide researchers toward an evidence-based treatment protocol for the prevention of oral mucositis. Frontiers Media S.A. 2021-07-16 /pmc/articles/PMC8757848/ /pubmed/35048034 http://dx.doi.org/10.3389/froh.2021.689386 Text en Copyright © 2021 Adnan, Yaroslavsky, Carroll, Selting, Juliano, London, Sonis, Duncan and Treister. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oral Health
Adnan, Ather
Yaroslavsky, Anna N.
Carroll, James D.
Selting, Wayne
Juliano, Amy F.
London, Wendy B.
Sonis, Stephen T.
Duncan, Christine N.
Treister, Nathaniel S.
The Path to an Evidence-Based Treatment Protocol for Extraoral Photobiomodulation Therapy for the Prevention of Oral Mucositis
title The Path to an Evidence-Based Treatment Protocol for Extraoral Photobiomodulation Therapy for the Prevention of Oral Mucositis
title_full The Path to an Evidence-Based Treatment Protocol for Extraoral Photobiomodulation Therapy for the Prevention of Oral Mucositis
title_fullStr The Path to an Evidence-Based Treatment Protocol for Extraoral Photobiomodulation Therapy for the Prevention of Oral Mucositis
title_full_unstemmed The Path to an Evidence-Based Treatment Protocol for Extraoral Photobiomodulation Therapy for the Prevention of Oral Mucositis
title_short The Path to an Evidence-Based Treatment Protocol for Extraoral Photobiomodulation Therapy for the Prevention of Oral Mucositis
title_sort path to an evidence-based treatment protocol for extraoral photobiomodulation therapy for the prevention of oral mucositis
topic Oral Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757848/
https://www.ncbi.nlm.nih.gov/pubmed/35048034
http://dx.doi.org/10.3389/froh.2021.689386
work_keys_str_mv AT adnanather thepathtoanevidencebasedtreatmentprotocolforextraoralphotobiomodulationtherapyforthepreventionoforalmucositis
AT yaroslavskyannan thepathtoanevidencebasedtreatmentprotocolforextraoralphotobiomodulationtherapyforthepreventionoforalmucositis
AT carrolljamesd thepathtoanevidencebasedtreatmentprotocolforextraoralphotobiomodulationtherapyforthepreventionoforalmucositis
AT seltingwayne thepathtoanevidencebasedtreatmentprotocolforextraoralphotobiomodulationtherapyforthepreventionoforalmucositis
AT julianoamyf thepathtoanevidencebasedtreatmentprotocolforextraoralphotobiomodulationtherapyforthepreventionoforalmucositis
AT londonwendyb thepathtoanevidencebasedtreatmentprotocolforextraoralphotobiomodulationtherapyforthepreventionoforalmucositis
AT sonisstephent thepathtoanevidencebasedtreatmentprotocolforextraoralphotobiomodulationtherapyforthepreventionoforalmucositis
AT duncanchristinen thepathtoanevidencebasedtreatmentprotocolforextraoralphotobiomodulationtherapyforthepreventionoforalmucositis
AT treisternathaniels thepathtoanevidencebasedtreatmentprotocolforextraoralphotobiomodulationtherapyforthepreventionoforalmucositis
AT adnanather pathtoanevidencebasedtreatmentprotocolforextraoralphotobiomodulationtherapyforthepreventionoforalmucositis
AT yaroslavskyannan pathtoanevidencebasedtreatmentprotocolforextraoralphotobiomodulationtherapyforthepreventionoforalmucositis
AT carrolljamesd pathtoanevidencebasedtreatmentprotocolforextraoralphotobiomodulationtherapyforthepreventionoforalmucositis
AT seltingwayne pathtoanevidencebasedtreatmentprotocolforextraoralphotobiomodulationtherapyforthepreventionoforalmucositis
AT julianoamyf pathtoanevidencebasedtreatmentprotocolforextraoralphotobiomodulationtherapyforthepreventionoforalmucositis
AT londonwendyb pathtoanevidencebasedtreatmentprotocolforextraoralphotobiomodulationtherapyforthepreventionoforalmucositis
AT sonisstephent pathtoanevidencebasedtreatmentprotocolforextraoralphotobiomodulationtherapyforthepreventionoforalmucositis
AT duncanchristinen pathtoanevidencebasedtreatmentprotocolforextraoralphotobiomodulationtherapyforthepreventionoforalmucositis
AT treisternathaniels pathtoanevidencebasedtreatmentprotocolforextraoralphotobiomodulationtherapyforthepreventionoforalmucositis

Ejemplares similares