Evolutionary paths to macrolide resistance in a Neisseria commensal converge on ribosomal genes through short sequence duplications

Neisseria commensals are an indisputable source of resistance for their pathogenic relatives. However, the evolutionary paths commensal species take to reduced susceptibility in this genus have been relatively underexplored. Here, we leverage in vitro selection as a powerful screen to identify the g...

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Detalles Bibliográficos
Autores principales: Raisman, Jordan C., Fiore, Michael A., Tomin, Lucille, Adjei, Joseph K. O., Aswad, Virginia X., Chu, Jonathan, Domondon, Christina J., Donahue, Ben A., Masciotti, Claudia A., McGrath, Connor G., Melita, Jo, Podbielski, Paul A., Schreiner, Madelyn R., Trumpore, Lauren J., Wengert, Peter C., Wrightstone, Emalee A., Hudson, André O., Wadsworth, Crista B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758062/
https://www.ncbi.nlm.nih.gov/pubmed/35025928
http://dx.doi.org/10.1371/journal.pone.0262370

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