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Innate-like NKp30(+)CD8(+) T cells armed with TCR/CAR target tumor heterogeneity
Intratumoral heterogeneity is frequently associated with tumor immune escape, with MHC-class I and antigen expression loss rendering tumor cells invisible to T cell killing, representing a major challenge for the design of successful adoptive transfer protocols for cancer immunotherapy. While CD8(+)...
Autores principales: | Correia, Margareta P., Stojanovic, Ana, Wels, Winfried S., Cerwenka, Adelheid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758178/ https://www.ncbi.nlm.nih.gov/pubmed/35036073 http://dx.doi.org/10.1080/2162402X.2021.1973783 |
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