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Innate-like NKp30(+)CD8(+) T cells armed with TCR/CAR target tumor heterogeneity

Intratumoral heterogeneity is frequently associated with tumor immune escape, with MHC-class I and antigen expression loss rendering tumor cells invisible to T cell killing, representing a major challenge for the design of successful adoptive transfer protocols for cancer immunotherapy. While CD8(+)...

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Detalles Bibliográficos
Autores principales: Correia, Margareta P., Stojanovic, Ana, Wels, Winfried S., Cerwenka, Adelheid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758178/
https://www.ncbi.nlm.nih.gov/pubmed/35036073
http://dx.doi.org/10.1080/2162402X.2021.1973783

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