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Chondroitin 6-sulphate is required for neuroplasticity and memory in ageing

Perineuronal nets (PNNs) are chondroitin sulphate proteoglycan-containing structures on the neuronal surface that have been implicated in the control of neuroplasticity and memory. Age-related reduction of chondroitin 6-sulphates (C6S) leads to PNNs becoming more inhibitory. Here, we investigated wh...

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Detalles Bibliográficos
Autores principales:	Yang, Sujeong, Gigout, Sylvain, Molinaro, Angelo, Naito-Matsui, Yuko, Hilton, Sam, Foscarin, Simona, Nieuwenhuis, Bart, Tan, Chin Lik, Verhaagen, Joost, Pizzorusso, Tommaso, Saksida, Lisa M., Bussey, Timothy M., Kitagawa, Hiroshi, Kwok, Jessica C. F., Fawcett, James W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758471/ https://www.ncbi.nlm.nih.gov/pubmed/34272488 http://dx.doi.org/10.1038/s41380-021-01208-9

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