Astroglial tracer BU99008 detects multiple binding sites in Alzheimer’s disease brain

With reactive astrogliosis being established as one of the hallmarks of Alzheimer’s disease (AD), there is high interest in developing novel positron emission tomography (PET) tracers to detect early astrocyte reactivity. BU99008, a novel astrocytic PET ligand targeting imidazoline-2 binding sites (...

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Detalles Bibliográficos
Autores principales: Kumar, Amit, Koistinen, Niina A., Malarte, Mona-Lisa, Nennesmo, Inger, Ingelsson, Martin, Ghetti, Bernardino, Lemoine, Laetitia, Nordberg, Agneta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758481/
https://www.ncbi.nlm.nih.gov/pubmed/33888872
http://dx.doi.org/10.1038/s41380-021-01101-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758481/
https://www.ncbi.nlm.nih.gov/pubmed/33888872
http://dx.doi.org/10.1038/s41380-021-01101-5

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