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APOEε4 potentiates the relationship between amyloid-β and tau pathologies

APOEε4 is the most well-established genetic risk factor for sporadic Alzheimer’s disease and is associated with cerebral amyloid-β. However, the association between APOEε4 and tau pathology, the other major proteinopathy of Alzheimer’s disease, has been controversial. Here, we sought to determine wh...

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Detalles Bibliográficos
Autores principales: Therriault, Joseph, Benedet, Andrea L., Pascoal, Tharick A., Mathotaarachchi, Sulantha, Savard, Melissa, Chamoun, Mira, Thomas, Emilie, Kang, Min Su, Lussier, Firoza, Tissot, Cecile, Soucy, Jean-Paul, Massarweh, Gassan, Rej, Soham, Saha-Chaudhuri, Paramita, Poirier, Judes, Gauthier, Serge, Rosa-Neto, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758492/
https://www.ncbi.nlm.nih.gov/pubmed/32161362
http://dx.doi.org/10.1038/s41380-020-0688-6