Cargando…
Machine learning optimized polygenic scores for blood cell traits identify sex-specific trajectories and genetic correlations with disease
Genetic association studies for blood cell traits, which are key indicators of health and immune function, have identified several hundred associations and defined a complex polygenic architecture. Polygenic scores (PGSs) for blood cell traits have potential clinical utility in disease risk predicti...
| Autores principales: | , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758502/ https://www.ncbi.nlm.nih.gov/pubmed/35072137 http://dx.doi.org/10.1016/j.xgen.2021.100086 |