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A biosynthetic pathway to aromatic amines that uses glycyl-tRNA as nitrogen donor
Aromatic amines in nature are typically installed with Glu or Gln as the nitrogen donor. Here we report a pathway that features glycyl-tRNA as the nitrogen donor. During the biosynthesis of pyrroloiminoquinone-type natural products such as ammosamide, peptide-aminoacyl tRNA ligases (PEARLs) append a...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758506/ https://www.ncbi.nlm.nih.gov/pubmed/34725492 http://dx.doi.org/10.1038/s41557-021-00802-2 |