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Rates and Patterns of Clonal Oncogenic Mutations in the Normal Human Brain

Although oncogenic mutations have been found in nondiseased, proliferative nonneural tissues, their prevalence in the human brain is unknown. Targeted sequencing of genes implicated in brain tumors in 418 samples derived from 110 individuals of varying ages, without tumor diagnoses, detected oncogen...

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Detalles Bibliográficos
Autores principales: Ganz, Javier, Maury, Eduardo A., Becerra, Basheer, Bizzotto, Sara, Doan, Ryan N., Kenny, Connor J., Shin, Taehwan, Kim, Junho, Zhou, Zinan, Ligon, Keith L., Lee, Eunjung Alice, Walsh, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758513/
https://www.ncbi.nlm.nih.gov/pubmed/34389641
http://dx.doi.org/10.1158/2159-8290.CD-21-0245