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Rates and Patterns of Clonal Oncogenic Mutations in the Normal Human Brain
Although oncogenic mutations have been found in nondiseased, proliferative nonneural tissues, their prevalence in the human brain is unknown. Targeted sequencing of genes implicated in brain tumors in 418 samples derived from 110 individuals of varying ages, without tumor diagnoses, detected oncogen...
Autores principales: | Ganz, Javier, Maury, Eduardo A., Becerra, Basheer, Bizzotto, Sara, Doan, Ryan N., Kenny, Connor J., Shin, Taehwan, Kim, Junho, Zhou, Zinan, Ligon, Keith L., Lee, Eunjung Alice, Walsh, Christopher A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758513/ https://www.ncbi.nlm.nih.gov/pubmed/34389641 http://dx.doi.org/10.1158/2159-8290.CD-21-0245 |
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