Ex vivo and in vivo suppression of SARS-CoV-2 with combinatorial AAV/RNAi expression vectors

Despite rapid development and deployment of vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), clinically relevant modalities to curb the pandemic by directly attacking the virus on a genetic level remain highly desirable and are urgently needed. Here we comprehensively i...

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Detalles Bibliográficos
Autores principales: Becker, Jonas, Stanifer, Megan Lynn, Leist, Sarah Rebecca, Stolp, Bettina, Maiakovska, Olena, West, Ande, Wiedtke, Ellen, Börner, Kathleen, Ghanem, Ali, Ambiel, Ina, Tse, Longping Victor, Fackler, Oliver Till, Baric, Ralph Steven, Boulant, Steeve, Grimm, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758558/
https://www.ncbi.nlm.nih.gov/pubmed/35038579
http://dx.doi.org/10.1016/j.ymthe.2022.01.024

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