Viral co-pathogens in COVID-19 acute respiratory syndrome – what did we learn from the first year of pandemic?

OBJECTIVE: : This study aimed to describe the distribution of respiratory pathogens and the occurrence of co-pathogens during the first year of the COVID-19 pandemic. METHODS: We used a multiplex polymerase chain reaction (PCR) panel targeting 23 microorganisms to analyze the oro-pharyngeal samples...

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Detalles Bibliográficos
Autores principales: Kriger, Or, Gefen-Halevi, Shiraz, Leshem, Eyal, Smollan, Gillian, Belausov, Natasha, Egbarye, Aseel, Khashab, Rawan, Odeh, Miran, Saffia, Adleen, Barak, Yuval, Hussein, Oswa Abu, Hamias, Rachel, Aharon, Yael, Alfandari, Jacqueline, Nemet, Ital, Kliker, Limor, Sherbany, Hilda, Mandelboim, Michal, Amit, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758566/
https://www.ncbi.nlm.nih.gov/pubmed/35038602
http://dx.doi.org/10.1016/j.ijid.2022.01.018
Descripción
Sumario:OBJECTIVE: : This study aimed to describe the distribution of respiratory pathogens and the occurrence of co-pathogens during the first year of the COVID-19 pandemic. METHODS: We used a multiplex polymerase chain reaction (PCR) panel targeting 23 microorganisms to analyze the oro-pharyngeal samples of patients admitted to our hospital with acute respiratory infection (ARI) between March 1, 2020, and February 28, 2021. We matched 40 to 50 patients who were SARS-CoV-2 positive and SARS-CoV-2 negative per month for age and sex. RESULTS: A total of 939 patients with multiplex PCR test results were included in the study. Respiratory pathogens where detected in only 8/476 (1.6%) patients with COVID-19 versus 87/463 (18.7%) patients with non–COVID-19 ARI patients. Diversity and rates of pathogens vastly differed from previous years but showed seasonal variance. CONCLUSION: Patients with SARS-CoV-2 infection presenting with ARI during the first year of the COVID-19 pandemic demonstrated paucity of respiratory co-pathogens.

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