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Characterization of phage resistance and phages capable of intestinal decolonization of carbapenem-resistant Klebsiella pneumoniae in mice

Carbapenem-resistant Klebsiella pneumoniae (CRKP) has emerged as a severe global health challenge. We isolate and characterize two previously unidentified lytic phages, P24 and P39, with large burst sizes active against ST11 KL64, a major CRKP lineage. P24 and P39 represent species of the genera Prz...

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Detalles Bibliográficos
Autores principales: Fang, Qingqing, Feng, Yu, McNally, Alan, Zong, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758719/
https://www.ncbi.nlm.nih.gov/pubmed/35027665
http://dx.doi.org/10.1038/s42003-022-03001-y

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