Molecular mechanism of agonism and inverse agonism in ghrelin receptor

Much effort has been invested in the investigation of the structural basis of G protein-coupled receptors (GPCRs) activation. Inverse agonists, which can inhibit GPCRs with constitutive activity, are considered useful therapeutic agents, but the molecular mechanism of such ligands remains insufficie...

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Detalles Bibliográficos
Autores principales: Qin, Jiao, Cai, Ye, Xu, Zheng, Ming, Qianqian, Ji, Su-Yu, Wu, Chao, Zhang, Huibing, Mao, Chunyou, Shen, Dan-Dan, Hirata, Kunio, Ma, Yanbin, Yan, Wei, Zhang, Yan, Shao, Zhenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758724/
https://www.ncbi.nlm.nih.gov/pubmed/35027551
http://dx.doi.org/10.1038/s41467-022-27975-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758724/
https://www.ncbi.nlm.nih.gov/pubmed/35027551
http://dx.doi.org/10.1038/s41467-022-27975-9

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