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Elucidating functional epitopes within the N-terminal region of malaria transmission blocking vaccine antigen Pfs230

Pfs230 is a leading malaria transmission blocking vaccine (TBV) candidate. Comprising 3135 amino acids (aa), the large size of Pfs230 necessitates the use of sub-fragments as vaccine immunogens. Therefore, determination of which regions induce functional antibody responses is essential. We previousl...

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Detalles Bibliográficos
Autores principales: Miura, Kazutoyo, Takashima, Eizo, Pham, Thao P., Deng, Bingbing, Zhou, Luwen, Huang, Wei-Chiao, Diouf, Ababacar, Gebremicale, Yonas T., Tachibana, Mayumi, Ishino, Tomoko, Richter King, C., Lovell, Jonathan F., Long, Carole A., Tsuboi, Takafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758780/
https://www.ncbi.nlm.nih.gov/pubmed/35027567
http://dx.doi.org/10.1038/s41541-021-00423-3