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Similar neuronal imprint and no cross-seeded fibrils in α-synuclein aggregates from MSA and Parkinson’s disease

Aggregated alpha-synuclein (α-syn) is a principal constituent of Lewy bodies (LBs) and glial cytoplasmic inclusions (GCIs) observed respectively inside neurons in Parkinson’s disease (PD) and oligodendrocytes in multiple system atrophy (MSA). Yet, the cellular origin, the pathophysiological role, an...

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Detalles Bibliográficos
Autores principales:	Laferrière, Florent, Claverol, Stéphane, Bezard, Erwan, De Giorgi, Francesca, Ichas, François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758785/ https://www.ncbi.nlm.nih.gov/pubmed/35027576 http://dx.doi.org/10.1038/s41531-021-00264-w

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