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Differential repression of Otx2 underlies the capacity of NANOG and ESRRB to induce germline entry

Primordial germ cells (PGCs) arise from cells of the post-implantation epiblast in response to cytokine signaling. PGC development can be recapitulated in vitro by differentiating epiblast-like cells (EpiLCs) into PGC-like cells (PGCLCs) through cytokine exposure. Interestingly, the cytokine require...

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Detalles Bibliográficos
Autores principales:	Vojtek, Matúš, Zhang, Jingchao, Sun, Juanjuan, Zhang, Man, Chambers, Ian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758940/ https://www.ncbi.nlm.nih.gov/pubmed/34971561 http://dx.doi.org/10.1016/j.stemcr.2021.11.013

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