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Cell position within human pluripotent stem cell colonies determines apical specialization via an actin cytoskeleton-based mechanism

Human pluripotent stem cells (hPSCs) grow as colonies with epithelial-like features including cell polarity and position-dependent features that contribute to symmetry breaking during development. Our study provides evidence that hPSC colonies exhibit position-dependent differences in apical structu...

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Detalles Bibliográficos
Autores principales: Kim, Youngju, Jang, Hwanseok, Seo, Kyubin, Kim, June Hoan, Lee, Boram, Cho, Hyo Min, Kim, Hyun Jung, Yang, Esther, Kim, Hyun, Gim, Jeong-An, Park, Yongdoo, Ryu, Jae Ryun, Sun, Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758941/
https://www.ncbi.nlm.nih.gov/pubmed/34919810
http://dx.doi.org/10.1016/j.stemcr.2021.11.005