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Cell position within human pluripotent stem cell colonies determines apical specialization via an actin cytoskeleton-based mechanism
Human pluripotent stem cells (hPSCs) grow as colonies with epithelial-like features including cell polarity and position-dependent features that contribute to symmetry breaking during development. Our study provides evidence that hPSC colonies exhibit position-dependent differences in apical structu...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758941/ https://www.ncbi.nlm.nih.gov/pubmed/34919810 http://dx.doi.org/10.1016/j.stemcr.2021.11.005 |