Early reactivation of clustered genes on the inactive X chromosome during somatic cell reprogramming

Reprogramming of murine female somatic cells to induced pluripotent stem cells (iPSCs) is accompanied by X chromosome reactivation (XCR), by which the inactive X chromosome (Xi) in female somatic cells becomes reactivated. However, how Xi initiates reactivation during reprogramming remains poorly de...

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Detalles Bibliográficos
Autores principales: Aizawa, Shiho, Nishimura, Ken, Mondejar, Gonzalo Seminario, Kumar, Arun, Bui, Phuong Linh, Tran, Yen Thi Hai, Kuno, Akihiro, Muratani, Masafumi, Kobayashi, Shin, Nabekura, Tsukasa, Shibuya, Akira, Sugihara, Eiji, Sato, Taka-Aki, Fukuda, Aya, Hayashi, Yohei, Hisatake, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758948/
https://www.ncbi.nlm.nih.gov/pubmed/34919813
http://dx.doi.org/10.1016/j.stemcr.2021.11.008

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