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Modulation by DREADD reveals the therapeutic effect of human iPSC-derived neuronal activity on functional recovery after spinal cord injury

Transplantation of neural stem/progenitor cells (NS/PCs) derived from human induced pluripotent stem cells (hiPSCs) is considered to be a promising therapy for spinal cord injury (SCI) and will soon be translated to the clinical phase. However, how grafted neuronal activity influences functional rec...

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Detalles Bibliográficos
Autores principales: Kitagawa, Takahiro, Nagoshi, Narihito, Kamata, Yasuhiro, Kawai, Momotaro, Ago, Kentaro, Kajikawa, Keita, Shibata, Reo, Sato, Yuta, Imaizumi, Kent, Shindo, Tomoko, Shinozaki, Munehisa, Kohyama, Jun, Shibata, Shinsuke, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758967/
https://www.ncbi.nlm.nih.gov/pubmed/35021049
http://dx.doi.org/10.1016/j.stemcr.2021.12.005