A clinically applicable gene expression–based score predicts resistance to induction treatment in acute myeloid leukemia

Prediction of resistant disease at initial diagnosis of acute myeloid leukemia (AML) can be achieved with high accuracy using cytogenetic data and 29 gene expression markers (Predictive Score 29 Medical Research Council; PS29MRC). Our aim was to establish PS29MRC as a clinically usable assay by usin...

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Detalles Bibliográficos
Autores principales: Moser, Christian, Jurinovic, Vindi, Sagebiel-Kohler, Sabine, Ksienzyk, Bianka, Batcha, Aarif M. N., Dufour, Annika, Schneider, Stephanie, Rothenberg-Thurley, Maja, Sauerland, Cristina M., Görlich, Dennis, Berdel, Wolfgang E., Krug, Utz, Mansmann, Ulrich, Hiddemann, Wolfgang, Braess, Jan, Spiekermann, Karsten, Greif, Philipp A., Vosberg, Sebastian, Metzeler, Klaus H., Kumbrink, Jörg, Herold, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Myeloid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759116/
https://www.ncbi.nlm.nih.gov/pubmed/34535016
http://dx.doi.org/10.1182/bloodadvances.2021004814

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