Transcription factor MEF2D is required for the maintenance of MLL-rearranged acute myeloid leukemia

Acute myeloid leukemia (AML) with MLL-rearrangement (MLL-r) comprises ∼10% of all AML cases and portends poor outcomes. Much remains uncovered on how MLL-r AML drives leukemia development while preventing cells from normal myeloid differentiation. Here, we identified that transcription factor MEF2D...

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Detalles Bibliográficos
Autores principales: Zhao, Lianzhong, Zhang, Pengcheng, Galbo, Phillip M., Zhou, Xinyue, Aryal, Sajesan, Qiu, Shaowei, Zhang, Hao, Zhou, Yang, Li, Chunliang, Zheng, Deyou, Bhatia, Ravi, Lu, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Myeloid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759131/
https://www.ncbi.nlm.nih.gov/pubmed/34597364
http://dx.doi.org/10.1182/bloodadvances.2021004469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759131/
https://www.ncbi.nlm.nih.gov/pubmed/34597364
http://dx.doi.org/10.1182/bloodadvances.2021004469

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