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Coevolving JAK2(V617F+)relapsed AML and donor T cells with PD-1 blockade after stem cell transplantation: an index case

Relapse of myeloproliferative neoplasms (MPNs) after allogeneic hematopoietic stem cell transplantation (HSCT) is associated with poor outcomes, as therapeutic approaches to reinstate effective graft-versus-leukemia (GVL) responses remain suboptimal. Immune escape through overexpression of PD-L1 in...

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Detalles Bibliográficos
Autores principales: Penter, Livius, Gohil, Satyen H., Huang, Teddy, Thrash, Emily M., Schmidt, Dominik, Li, Shuqiang, Severgnini, Mariano, Neuberg, Donna, Hodi, F. Stephen, Livak, Kenneth J., Zeiser, Robert, Bachireddy, Pavan, Wu, Catherine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759138/
https://www.ncbi.nlm.nih.gov/pubmed/34432868
http://dx.doi.org/10.1182/bloodadvances.2021004335