Cargando…

A Two-Stage Adaptive Laboratory Evolution Strategy to Enhance Docosahexaenoic Acid Synthesis in Oleaginous Thraustochytrid

Thraustochytrid is a promising algal oil resource with the potential to meet the demand for docosahexaenoic acid (DHA). However, oils with high DHA content produced by genetic modified thraustochytrids are not accepted by the food and pharmaceutical industries in many countries. Therefore, in order...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Sen, Wan, Weijian, Wang, Zhuojun, Zhang, Huidan, Liu, Huan, Arunakumara, K. K. I. U., Cui, Qiu, Song, Xiaojin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Nutrition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759201/ https://www.ncbi.nlm.nih.gov/pubmed/35036411 http://dx.doi.org/10.3389/fnut.2021.795491

Ejemplares similares

Cocktail biosynthesis of triacylglycerol by rational modulation of diacylglycerol acyltransferases in industrial oleaginous Aurantiochytrium
por: Lan, Chuanzeng, et al.
Publicado: (2021)

A phospholipid:diacylglycerol acyltransferase is involved in the regulation of phospholipids homeostasis in oleaginous Aurantiochytrium sp.
por: Zhang, Huidan, et al.
Publicado: (2023)

Screening of new British thraustochytrids isolates for docosahexaenoic acid (DHA) production
por: Marchan, Loris Fossier, et al.
Publicado: (2017)

Draft genome sequence of the docosahexaenoic acid producing thraustochytrid Aurantiochytrium sp. T66
por: Liu, Bin, et al.
Publicado: (2016)

Response surface optimization of culture medium for enhanced docosahexaenoic acid production by a Malaysian thraustochytrid
por: Manikan, Vidyah, et al.
Publicado: (2015)

Draft genome sequence of a docosahexaenoic-acid-producing marine protist, thraustochytrid strain 12B
por: Sahara, Takehiko, et al.
Publicado: (2023)

Production, Biosynthesis, and Commercial Applications of Fatty Acids From Oleaginous Fungi
por: Zhang, Xin-Yue, et al.
Publicado: (2022)

Docosahexaenoic Acid Is Naturally Concentrated at the sn-2 Position in Triacylglycerols of the Australian Thraustochytrid Aurantiochytrium sp. Strain TC 20
por: Lee-Chang, Kim Jye, et al.
Publicado: (2021)

PUFA-synthase-specific PPTase enhanced the polyunsaturated fatty acid biosynthesis via the polyketide synthase pathway in Aurantiochytrium
por: Wang, Sen, et al.
Publicado: (2020)

Docosahexaenoic acid supplementation in gestational diabetes mellitus and neonatal metabolic health biomarkers
por: Xu, Ya-Jie, et al.
Publicado: (2023)

Characterization of NAD(+)/NADP(+)-Specific Isocitrate Dehydrogenases From Oleaginous Fungus Mortierella alpina Involved in Lipid Accumulation
por: Tang, Xin, et al.
Publicado: (2021)

Encapsulation of Docosahexaenoic Acid Oil Substantially Improves the Oxylipin Profile of Rat Tissues
por: Wang, Jun, et al.
Publicado: (2022)

Assessment of Fatty Acids Profile and Omega-3 Polyunsaturated Fatty Acid Production by the Oleaginous Marine Thraustochytrid Aurantiochytrium sp. T66 Cultivated on Volatile Fatty Acids
por: Patel, Alok, et al.
Publicado: (2020)

Flow Cytometry for Rapid Enumeration and Biomass Quantification of Thraustochytrids in Coastal Seawaters
por: Duan, Yingbo, et al.
Publicado: (2018)

Engineering xylose metabolism in thraustochytrid T18
por: Merkx-Jacques, Alexandra, et al.
Publicado: (2018)

Impact of Arachidonic and Docosahexaenoic Acid Supplementation on Neural and Immune Development in the Young Pig
por: Hahn, Kaylee E., et al.
Publicado: (2020)

Culturable Diversity of Thraustochytrids from Coastal Waters of Qingdao and Their Fatty Acids
por: Bai, Mohan, et al.
Publicado: (2022)

Tricarboxylate Citrate Transporter of an Oleaginous Fungus Mucor circinelloides WJ11: From Function to Structure and Role in Lipid Production
por: Yang, Wu, et al.
Publicado: (2021)

ATP Drives Efficient Terpene Biosynthesis in Marine Thraustochytrids
por: Zhang, Aiqing, et al.
Publicado: (2021)

Rewiring the Metabolic Network to Increase Docosahexaenoic Acid Productivity in Crypthecodinium cohnii by Fermentation Supernatant-Based Adaptive Laboratory Evolution
por: Liu, Liangsen, et al.
Publicado: (2022)

Method Development Progress in Genetic Engineering of Thraustochytrids
por: Rau, E-Ming, et al.
Publicado: (2021)

Effect of Eicosapentaenoic Acid and Docosahexaenoic Acid on Myogenesis and Mitochondrial Biosynthesis during Murine Skeletal Muscle Cell Differentiation
por: Hsueh, Tun-Yun, et al.
Publicado: (2018)

Assessment of lipid composition and eicosapentaenoic acid/docosahexaenoic acid bioavailability in fish oil obtained through different enrichment methods
por: Song, Rongzhen, et al.
Publicado: (2023)

Physicochemical Characteristics of Protein Isolated from Thraustochytrid Oilcake
por: Nham Tran, Thi Linh, et al.
Publicado: (2020)

Diverse Enzymes With Industrial Applications in Four Thraustochytrid Genera
por: Lin, Hsiu-Chin, et al.
Publicado: (2020)

Nannochloropsis Genomes Reveal Evolution of Microalgal Oleaginous Traits
por: Wang, Dongmei, et al.
Publicado: (2014)

A Dietary Supplement Containing Micronutrients, Phosphatidylserine, and Docosahexaenoic Acid Counteracts Cognitive Impairment in D-Galactose-Induced Aged Rats
por: Ren, Qian, et al.
Publicado: (2022)

Differential effects of high dose omega-3 fatty acids on metabolism and inflammation in patients with obesity: eicosapentaenoic and docosahexaenoic acid supplementation
por: Borja-Magno, Angélica, et al.
Publicado: (2023)

Role of long-chain polyunsaturated fatty acids, eicosapentaenoic and docosahexaenoic, in the regulation of gene expression during the development of obesity: a systematic review
por: Sandoval, Cristian, et al.
Publicado: (2023)

The Laboratory and Clinical Perspectives of Magnesium Imbalance
por: Ab Rahim, Siti Nadirah, et al.
Publicado: (2023)

Elemental Composition and Cell Mass Quantification of Cultured Thraustochytrids Unveil Their Large Contribution to Marine Carbon Pool
por: Sen, Biswarup, et al.
Publicado: (2021)

Dietary Phospholipid-Bound Conjugated Linoleic Acid and Docosahexaenoic Acid Incorporation Into Fetal Liver and Brain Modulates Fatty Acid and N-Acylethanolamine Profiles
por: Murru, Elisabetta, et al.
Publicado: (2022)

Isolation, Characterization and Biotechnological Potentials of Thraustochytrids from Icelandic Waters
por: Stefánsson, Magnús Örn, et al.
Publicado: (2019)

Co-production of DHA and squalene by thraustochytrid from forest biomass
por: Patel, Alok, et al.
Publicado: (2020)

An acidic morpholine derivative containing glyceride from thraustochytrid, Aurantiochytrium
por: Kaya, Kunimitsu, et al.
Publicado: (2021)

Fatty acid production of thraustochytrids from Saudi Arabian mangroves
por: Abdel-Wahab, Mohamed A., et al.
Publicado: (2021)

Antarctic Thraustochytrids as Sources of Carotenoids and High-Value Fatty Acids
por: Leyton, Allison, et al.
Publicado: (2021)

Docosahexaenoic and Eicosapentaenoic Intervention Modifies Plasma and Erythrocyte Omega-3 Fatty Acid Profiles But Not the Clinical Course of Children With Autism Spectrum Disorder: A Randomized Control Trial
por: de la Torre-Aguilar, Maria Jose, et al.
Publicado: (2022)

Long Chain Polyunsaturated Fatty Acids Docosahexaenoic Acid and Arachidonic Acid Supplementation in the Suckling and the Post-weaning Diet Influences the Immune System Development of T Helper Type-2 Bias Brown Norway Rat Offspring
por: Patel, Dhruvesh, et al.
Publicado: (2021)

Comparison of Cell Disruption Methods for Improving Lipid Extraction from Thraustochytrid Strains
por: Byreddy, Avinesh R., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_br0clhl3oh0hl69ikfnghjajq7