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Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression

BACKGROUND: Epigenetic clocks use DNA methylation (DNAm) levels of specific sets of CpG dinucleotides to accurately predict individual chronological age. A popular application of these clocks is to explore whether the deviation of predicted age from chronological age is associated with disease pheno...

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Detalles Bibliográficos
Autores principales:	Jonkman, Thomas H., Dekkers, Koen F., Slieker, Roderick C., Grant, Crystal D., Ikram, M. Arfan, van Greevenbroek, Marleen M. J., Franke, Lude, Veldink, Jan H., Boomsma, Dorret I., Slagboom, P. Eline, Consortium, B. I. O. S., Heijmans, Bastiaan T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759260/ https://www.ncbi.nlm.nih.gov/pubmed/35031073 http://dx.doi.org/10.1186/s13059-021-02585-8

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