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EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3
BACKGROUND: Gliomas are the most common malignant primary brain tumours with a highly immunosuppressive tumour microenvironment (TME) and poor prognosis. Circular RNAs (circRNA), a newly found type of endogenous noncoding RNA, characterized by high stability, abundance, conservation, have been shown...
Autores principales: | Pan, Ziwen, Zhao, Rongrong, Li, Boyan, Qi, Yanhua, Qiu, Wei, Guo, Qindong, Zhang, Shouji, Zhao, Shulin, Xu, Hao, Li, Ming, Gao, Zijie, Fan, Yang, Xu, Jianye, Wang, Huizhi, Wang, Shaobo, Qiu, Jiawei, Wang, Qingtong, Guo, Xing, Deng, Lin, Zhang, Ping, Xue, Hao, Li, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759291/ https://www.ncbi.nlm.nih.gov/pubmed/35031058 http://dx.doi.org/10.1186/s12943-021-01485-6 |
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